Friday, November 30, 2012

WFU Cancer Research Sparks Cover Story

The work of a team of Wake Forest University researchers developing a novel drug for prostate cancer treatment is featured on the cover of the Nov. 26 issue of the Journal of Medicinal Chemistry.

George Kulik, an associate professor of cancer biology, Mark Welker, the William L. Poteat Professor of Chemistry, and Freddie Salsbury, an associate professor of physics, led an interdisciplinary team with expertise in computational physics, synthetic chemistry and cancer biology.

All cells, both normal and diseased, rely on the PI3K cell signaling pathway for growth, so inhibiting the pathway selectively for cancer cells has long been a challenge for scientists in the fight against cancer. While turning PI3K inhibitors loose in the body would prevent the spread of cancer, doing so would also inhibit growth in lots of cells.

To effectively use this strategy in the treatment of cancer, the Wake Forest team had to target these inhibitors to specific kinds of cells. Using prostate cells as the target, they selected a protein that is specifically recognized by prostate cells and attach that protein to a PI3K inhibitor. Read more.


65 comments:

  1. Your article is actually excellent. Thanks for posting this helpful info. It actually helped me!!

    free dissertation proposal examples

    ReplyDelete
  2. Anyone who believes they have been a target this type of attack should immediately contact their financial louis vuitton outlet institutions and local FBI office, and promptly report it to the Internet Crime Complaint Center (IC3) Web site. The IC3 complaint database links complaints together to refer them to cartier replica the appropriate law enforcement agency for case consideration. The IC3 also uses rolex datejust replica complaint information to identify emerging trends and patterns.

    ReplyDelete
  3. Some people considered that it is very difficult to write effective essay paper which not only convey the message but also let the reader to appreciate your writing skills. But now it is quite easy to visit our site where writers offer their essay writing services which is available throughout the world anytime by just one click away.

    ReplyDelete
  4. Jigsaw Perform ground pad tiles are in your doorway within two days in Uk. These tend to be dispatched within twenty four hours and are an absolute must have for your own play floor; these play ground tiles are simple to clean too. JIGSAW PLAYGROUND MAT TILES

    ReplyDelete
  5. Thanks for taking the time to discuss this, I feel about it and love learning more on this topic. If possible, as you gain expertise, would you mind updating your blog with more information? It is extremely helpful for me.
    friv2planet.com , juegosfrivol.com , friv400game.com

    ReplyDelete
  6. every year a number of people True Healing Self Healing are die due to cancer diseases.We should be take more steps for save life.
    Thank

    ReplyDelete
  7. Oh! What a brilliant job you’ve accomplished here. All the facts on this topic are available in this post. I have not read any article up till now that tells every little fact about a certain topic. You must be very proud of yourself. Keep this up and you shall become the best writer ever.Brazilian honeymoon packages

    ReplyDelete
  8. Hello
    Kite Projects provides the best and cheap Bespoke Stainless Steel Handrails and Stainless Steel Ladders Provider in Uk. Call us now 01962 886290 to get information grp

    ReplyDelete
  9. This informative article will help those who read and Thanks for sharing this great info with everyone.texas website design

    ReplyDelete
  10. Video of Root Bridge Provides cellular confinement system specifically designed and sold for Geoweb tree root protection.Call to know at 01962 882020 about Root Bridge System

    ReplyDelete
  11. I could get an interesting topic to read through this article. Thanks for the share about the scrambled eggs.glyphicon

    ReplyDelete
  12. This is a wonderful article, Given order t shirts so much info in it, These type of articles keeps the users interest in the website, and keep on sharing

    ReplyDelete
  13. This content is simply exciting and creative. I have been deciding on a institutional move and this has helped me with one aspect.best refinance home mortgage loan

    ReplyDelete
  14. This was nice you'll get through it thanks for coming out to people this must've been Costa Calida a hard expierience but don't worry something good will come out of this somehow

    ReplyDelete
  15. It is terribly simple to finding United States as we generally tend to pest control in tucson rectangular measure at your city or nearest locations.

    ReplyDelete
  16. Good job and bunch of thanks for this valuable post. ShowBox Download

    ReplyDelete
  17. I want you to thank for your time of this wonderful read!!! I definately enjoy every lowest mortgage rates little bit of it and I have you bookmarked to check out new stuff of your blog a must read blog!

    ReplyDelete

  18. You have explored a great place. This is the remains of the lava that had ones exploded millions of years . The read that has been shared has given us a very good travel wrongful termination experience. Thank you for the post. I want to read more from you .

    ReplyDelete
  19. Hy!
    Thanks again for introducing mortgage broker Garden statues me to this amazing studio! It was fun creating and catching up with blogging friends! And I love how your banner turned out.

    ReplyDelete

  20. اليك بعض خيارات شركة تنظيف منازل بالدمامالتي تجعلك تستمتع بجو نقي ونظيف
    تعطي لك شركة تنظيف موكيت بالدمامبرنامج التنظيف الداخلي الا وهو برنامج تنظيف شامل وعالي الدقة وذات جودة عالية لاعمال تنظيف الفلل بالرياض وهو يكون مختص بكل شئ داخل الفلل من اثاث وسجاد وانتريهات وتنظيف الرفائع والانتيك والتحف والنجف كل مشتملات الفلل .
    شركة تنظيف كنب بالدمام كما انها تعطي برنامج التنظيف الخارجي ويتم هذا حسب رغبة عملائنا ويشمل تنظيف واجهات زجاجية او حجريه وتنظيف جناين الفلل واستعادة منزلك براق داخليا وخارجيا ويتم ذلك علي ايدي خبراء يتمتعون بدرجة عالية من الكفاءة والتدريب الجيد علي القيام بكافة اعمال التنظيف .
    شركة تنظيف واجهات حجر بالدمام
    شركة تنظيف واجهات وزجاج بالدمام
    شركة عزل اسطح بالدمام

    ReplyDelete
  21. i know yes yes i yes we all visited this part of the word last year - stunning scenery and colours, and amazing bird life. The valley of Bezirgan, above Kalkan, is a real treasure to be explored and refinancing a home mortgage. As the writer says, the trekking is superb -but it wrecked my aging knees!

    ReplyDelete
  22. Hi, I'm joining Cancer Research UK's Race for Life this year. Please join the fight by digging deep and sponsoring me - it's quick, easy and totally secure. Events like this are vital in funding Cancer Research UK's life-saving work into preventing, diagnosing and treating cancer. By sponsoring me, we can unite and create an
    dissertation Writing Service

    ReplyDelete
  23. We would love every single child thank you for the efforts you receive created this information. I really hope exactly the same best carry out originating from a person in the future simultaneously. These days right now just click as well as follow-up check cashing Thanks for the good post.

    ReplyDelete

  24. عملائنا الكرام اذا كنت تبحث عن افضل واقوي شركة شركة تركيب اثاث ايكيا بالرياضفى هذا المجال كما انها تتميز بالصدارة بين الكثير من الشركات المتواجدة في الرياض
    شركة تركيب اثاث ايكيا بالرياض
    كما اننا نتميز عن باقي الشركات بأننا لدينا افضل الطرق وافضل الادوات والمعدات فى تركيب غرف النوم الصيني

    كما اننا متقدمين عملائنا الكرام بتقديم افضل خدمات فني تركيب اثاث ايكيا بالرياضمع توفير امهر الفنيين في تركيب اثاث ايكيا كما اننا نعلم جيدا تعدد حاجات عملائنا من احتياج الفنيين والمتخصصين في عمليات فك وتركيب اثاث ايكيا بالرياض واحتاجهم لتواجد المساعدين لانجاز مهامهم بدقة وعلي اكمل وجة ممكن
    كما اننا نقدم العديد من الديكورات المختلفة والتصميمات الساحرة واحدث الالوان العصرية التي لن تجدوها الا من خلال شركة تركيب اثاث ايكيا بالرياض كما اننا نوفرها بأحدث الموديلات التي تتناسب مع احتياجات جميع عملائنا
    فأننا نحيط علمكم اذا كنت تريد تركيب اي اثاث في منزلك فلديك
    لزيارة موقعنا
    https://lwmt4.com/%D8%B4%D8%B1%D9%83%D8%A9-%D8%AA%D8%B1%D9%83%D9%8A%D8%A8-%D8%A7%D8%AB%D8%A7%D8%AB-%D8%A7%D9%8A%D9%83%D9%8A%D8%A7-%D8%A8%D8%A7%D9%84%D8%B1%D9%8A%D8%A7%D8%B6/

    ReplyDelete
  25. Good article writing. I will be for this reason blown away to observe this unique area. We'd happen to be accurately choosing. Bless you for the purpose of this present and even you need to keep going beneficial financial job. Seriously amazing present! I really learned this unique an incredible amount of informative. I'd like in an effort to endorse people whom unfortunately you need to hold referring to this sorts of records. At this moment check this mysql backup Bless you for the purpose of superior advice.

    ReplyDelete

  26. Good ad! Utilizing kudos appreciably considerably towards your ad not to mention web-site showing everywhere on. The other half moreover That I really enjoy any ad. Kudos significantly when it comes to proving a good content. Considered know an individual's persistence including I am patiently waiting an added compose. In the present day carry out the boston red sox tickets Always keep posting including kudos significantly thoroughly work.

    ReplyDelete
  27. CyberFlix TV merupakan antara aplikasi android yang wajib dimiliki untuk pengguna android device yang gemar untuk menonton Movie dan TV Show dengan kualiti yang sangat baik beserta inscriptions Cyberflix TV

    ReplyDelete
  28. GBWhatsapp goes with heaps of features and significantly greater improvement. GBWhatsapp have various new whatsapp gbsubjects and assurance.

    ReplyDelete
  29. cyberflix tv apk installs Cyberflix on your android smartphone and tablet.

    ReplyDelete
  30. Oceanofmobile
    Do you want to crack your softwares or want any generator and activator for personal computers and mac. Get serial keys and mode of any software to activate
    oceanofmobile.com

    ReplyDelete
  31. It is always blend with latest movies, TV shows and other videos. Cyberflix Tv always keep its database updated with new content.

    ReplyDelete
  32. Great content! Really informative and worth reading. Looking forward to more like this. To read informative articles like this please visit an amazing site Litlisted

    ReplyDelete
  33. Keep posting articles like this.It was an amazing read. To stream online movies for free, download this application Cyberflix TV

    ReplyDelete
  34. Know how to type degree symbol on any device Degree Symbol

    ReplyDelete
  35. hello sir,
    thanks for giving that type of information. Really enjoyed this blog post. Really looking forward to reading more. Much obliged.
    digital marketing company in delhi

    ReplyDelete
  36. Thanks for the article may be useful for everything
    App Developers in Noida

    ReplyDelete
  37. This is really great work. Thank you for sharing such useful information here in the blog. This really is excellent function. Thanks, with regard to discussing this kind of helpful info within your blog. You can now click here construction company westchester county Thanks greatly with regard to good publish.

    ReplyDelete
  38. I feel happy about and learning more about this topic. keep sharing your information regularly for my future reference. This content creates a new hope and inspiration with in me. Thanks for sharing article like this. the information which you have provided is better then other blog.
    Best IELTS Coaching in Dwarka

    ReplyDelete
  39. Hey Admin,
    I really appreciate your effort of sharing information with us. Your article never fails to add useful information to my knowledge. Thanks for sharing with us.
    UI Development Services

    ReplyDelete
  40. I found a lot of valuable information in your article, it’s really helpful for me, am suggest to my all dear friend to visit this blog and collect this valuable information, I really happy to say this keep sharing this type of blog, I really like to read this, I hope I will see you again with this type of valuable information, thank you so much for read my comment I will suggest to you all comment reader please deeply read this blog and collect this useful information, if any one searching the website designing company in India please come on my website ogeninfo, we are working in 5 year on this field, we are complete your all type project like website designing & web development and PPC.
    Web Designing Company in Delhi

    ReplyDelete
  41. Your blog give me a lot of valuable information, I really like to read your article, I will suggest to my all dear friend to visit this blog and collect this useful information, keep sharing like this type useful blog, I am really happy to say this am really enjoy to read this article, thank you so much for share this helpful information with us, if any one need a shipping company in India to shift you product, we are shift you product with care and faster if you need it so please come on my website Yhcargoindia, thanks to read my comment.
    Sea Freight Company in India

    ReplyDelete

  42. Thank you for this excellent read!! I definitely loved every little bit of it. Cheers for the information.
    This is the perfect blog for anyone who wants to know about this topic.
    You know so much it's almost hard to argue with you
    Buy Products TreasureBox

    ReplyDelete
  43. Top Law Firms in the United Kingdom When we need a law firm, we have the expectation that this law firm will support us and guide us in such a way that we can find out any solution under the legal framework. But the problem generates when we cannot find such a legal firm or law firm with such specialties that are required for that specific issue.

    ReplyDelete