Friday, November 30, 2012

WFU Cancer Research Sparks Cover Story

The work of a team of Wake Forest University researchers developing a novel drug for prostate cancer treatment is featured on the cover of the Nov. 26 issue of the Journal of Medicinal Chemistry.

George Kulik, an associate professor of cancer biology, Mark Welker, the William L. Poteat Professor of Chemistry, and Freddie Salsbury, an associate professor of physics, led an interdisciplinary team with expertise in computational physics, synthetic chemistry and cancer biology.

All cells, both normal and diseased, rely on the PI3K cell signaling pathway for growth, so inhibiting the pathway selectively for cancer cells has long been a challenge for scientists in the fight against cancer. While turning PI3K inhibitors loose in the body would prevent the spread of cancer, doing so would also inhibit growth in lots of cells.

To effectively use this strategy in the treatment of cancer, the Wake Forest team had to target these inhibitors to specific kinds of cells. Using prostate cells as the target, they selected a protein that is specifically recognized by prostate cells and attach that protein to a PI3K inhibitor. Read more.


124 comments:

  1. Your article is actually excellent. Thanks for posting this helpful info. It actually helped me!!

    free dissertation proposal examples

    ReplyDelete
  2. Anyone who believes they have been a target this type of attack should immediately contact their financial louis vuitton outlet institutions and local FBI office, and promptly report it to the Internet Crime Complaint Center (IC3) Web site. The IC3 complaint database links complaints together to refer them to cartier replica the appropriate law enforcement agency for case consideration. The IC3 also uses rolex datejust replica complaint information to identify emerging trends and patterns.

    ReplyDelete
  3. Some people considered that it is very difficult to write effective essay paper which not only convey the message but also let the reader to appreciate your writing skills. But now it is quite easy to visit our site where writers offer their essay writing services which is available throughout the world anytime by just one click away.

    ReplyDelete
  4. Jigsaw Perform ground pad tiles are in your doorway within two days in Uk. These tend to be dispatched within twenty four hours and are an absolute must have for your own play floor; these play ground tiles are simple to clean too. JIGSAW PLAYGROUND MAT TILES

    ReplyDelete
  5. Thanks for taking the time to discuss this, I feel about it and love learning more on this topic. If possible, as you gain expertise, would you mind updating your blog with more information? It is extremely helpful for me.
    friv2planet.com , juegosfrivol.com , friv400game.com

    ReplyDelete
  6. every year a number of people True Healing Self Healing are die due to cancer diseases.We should be take more steps for save life.
    Thank

    ReplyDelete
  7. Oh! What a brilliant job you’ve accomplished here. All the facts on this topic are available in this post. I have not read any article up till now that tells every little fact about a certain topic. You must be very proud of yourself. Keep this up and you shall become the best writer ever.Brazilian honeymoon packages

    ReplyDelete
  8. Hello
    Kite Projects provides the best and cheap Bespoke Stainless Steel Handrails and Stainless Steel Ladders Provider in Uk. Call us now 01962 886290 to get information grp

    ReplyDelete
  9. This informative article will help those who read and Thanks for sharing this great info with everyone.texas website design

    ReplyDelete
  10. Video of Root Bridge Provides cellular confinement system specifically designed and sold for Geoweb tree root protection.Call to know at 01962 882020 about Root Bridge System

    ReplyDelete
  11. I could get an interesting topic to read through this article. Thanks for the share about the scrambled eggs.glyphicon

    ReplyDelete
  12. This is a wonderful article, Given order t shirts so much info in it, These type of articles keeps the users interest in the website, and keep on sharing

    ReplyDelete
  13. This content is simply exciting and creative. I have been deciding on a institutional move and this has helped me with one aspect.best refinance home mortgage loan

    ReplyDelete
  14. This was nice you'll get through it thanks for coming out to people this must've been Costa Calida a hard expierience but don't worry something good will come out of this somehow

    ReplyDelete
  15. It is terribly simple to finding United States as we generally tend to pest control in tucson rectangular measure at your city or nearest locations.

    ReplyDelete
  16. Good job and bunch of thanks for this valuable post. ShowBox Download

    ReplyDelete
  17. I want you to thank for your time of this wonderful read!!! I definately enjoy every lowest mortgage rates little bit of it and I have you bookmarked to check out new stuff of your blog a must read blog!

    ReplyDelete

  18. You have explored a great place. This is the remains of the lava that had ones exploded millions of years . The read that has been shared has given us a very good travel wrongful termination experience. Thank you for the post. I want to read more from you .

    ReplyDelete
  19. Hy!
    Thanks again for introducing mortgage broker Garden statues me to this amazing studio! It was fun creating and catching up with blogging friends! And I love how your banner turned out.

    ReplyDelete

  20. اليك بعض خيارات شركة تنظيف منازل بالدمامالتي تجعلك تستمتع بجو نقي ونظيف
    تعطي لك شركة تنظيف موكيت بالدمامبرنامج التنظيف الداخلي الا وهو برنامج تنظيف شامل وعالي الدقة وذات جودة عالية لاعمال تنظيف الفلل بالرياض وهو يكون مختص بكل شئ داخل الفلل من اثاث وسجاد وانتريهات وتنظيف الرفائع والانتيك والتحف والنجف كل مشتملات الفلل .
    شركة تنظيف كنب بالدمام كما انها تعطي برنامج التنظيف الخارجي ويتم هذا حسب رغبة عملائنا ويشمل تنظيف واجهات زجاجية او حجريه وتنظيف جناين الفلل واستعادة منزلك براق داخليا وخارجيا ويتم ذلك علي ايدي خبراء يتمتعون بدرجة عالية من الكفاءة والتدريب الجيد علي القيام بكافة اعمال التنظيف .
    شركة تنظيف واجهات حجر بالدمام
    شركة تنظيف واجهات وزجاج بالدمام
    شركة عزل اسطح بالدمام

    ReplyDelete
  21. i know yes yes i yes we all visited this part of the word last year - stunning scenery and colours, and amazing bird life. The valley of Bezirgan, above Kalkan, is a real treasure to be explored and refinancing a home mortgage. As the writer says, the trekking is superb -but it wrecked my aging knees!

    ReplyDelete
  22. Hi, I'm joining Cancer Research UK's Race for Life this year. Please join the fight by digging deep and sponsoring me - it's quick, easy and totally secure. Events like this are vital in funding Cancer Research UK's life-saving work into preventing, diagnosing and treating cancer. By sponsoring me, we can unite and create an
    dissertation Writing Service

    ReplyDelete
  23. We would love every single child thank you for the efforts you receive created this information. I really hope exactly the same best carry out originating from a person in the future simultaneously. These days right now just click as well as follow-up check cashing Thanks for the good post.

    ReplyDelete

  24. عملائنا الكرام اذا كنت تبحث عن افضل واقوي شركة شركة تركيب اثاث ايكيا بالرياضفى هذا المجال كما انها تتميز بالصدارة بين الكثير من الشركات المتواجدة في الرياض
    شركة تركيب اثاث ايكيا بالرياض
    كما اننا نتميز عن باقي الشركات بأننا لدينا افضل الطرق وافضل الادوات والمعدات فى تركيب غرف النوم الصيني

    كما اننا متقدمين عملائنا الكرام بتقديم افضل خدمات فني تركيب اثاث ايكيا بالرياضمع توفير امهر الفنيين في تركيب اثاث ايكيا كما اننا نعلم جيدا تعدد حاجات عملائنا من احتياج الفنيين والمتخصصين في عمليات فك وتركيب اثاث ايكيا بالرياض واحتاجهم لتواجد المساعدين لانجاز مهامهم بدقة وعلي اكمل وجة ممكن
    كما اننا نقدم العديد من الديكورات المختلفة والتصميمات الساحرة واحدث الالوان العصرية التي لن تجدوها الا من خلال شركة تركيب اثاث ايكيا بالرياض كما اننا نوفرها بأحدث الموديلات التي تتناسب مع احتياجات جميع عملائنا
    فأننا نحيط علمكم اذا كنت تريد تركيب اي اثاث في منزلك فلديك
    لزيارة موقعنا
    https://lwmt4.com/%D8%B4%D8%B1%D9%83%D8%A9-%D8%AA%D8%B1%D9%83%D9%8A%D8%A8-%D8%A7%D8%AB%D8%A7%D8%AB-%D8%A7%D9%8A%D9%83%D9%8A%D8%A7-%D8%A8%D8%A7%D9%84%D8%B1%D9%8A%D8%A7%D8%B6/

    ReplyDelete
  25. Good article writing. I will be for this reason blown away to observe this unique area. We'd happen to be accurately choosing. Bless you for the purpose of this present and even you need to keep going beneficial financial job. Seriously amazing present! I really learned this unique an incredible amount of informative. I'd like in an effort to endorse people whom unfortunately you need to hold referring to this sorts of records. At this moment check this mysql backup Bless you for the purpose of superior advice.

    ReplyDelete

  26. Good ad! Utilizing kudos appreciably considerably towards your ad not to mention web-site showing everywhere on. The other half moreover That I really enjoy any ad. Kudos significantly when it comes to proving a good content. Considered know an individual's persistence including I am patiently waiting an added compose. In the present day carry out the boston red sox tickets Always keep posting including kudos significantly thoroughly work.

    ReplyDelete
  27. CyberFlix TV merupakan antara aplikasi android yang wajib dimiliki untuk pengguna android device yang gemar untuk menonton Movie dan TV Show dengan kualiti yang sangat baik beserta inscriptions Cyberflix TV

    ReplyDelete
  28. GBWhatsapp goes with heaps of features and significantly greater improvement. GBWhatsapp have various new whatsapp gbsubjects and assurance.

    ReplyDelete
  29. cyberflix tv apk installs Cyberflix on your android smartphone and tablet.

    ReplyDelete
  30. Oceanofmobile
    Do you want to crack your softwares or want any generator and activator for personal computers and mac. Get serial keys and mode of any software to activate
    oceanofmobile.com

    ReplyDelete
  31. It is always blend with latest movies, TV shows and other videos. Cyberflix Tv always keep its database updated with new content.

    ReplyDelete
  32. Great content! Really informative and worth reading. Looking forward to more like this. To read informative articles like this please visit an amazing site Litlisted

    ReplyDelete
  33. Keep posting articles like this.It was an amazing read. To stream online movies for free, download this application Cyberflix TV

    ReplyDelete
  34. Know how to type degree symbol on any device Degree Symbol

    ReplyDelete
  35. hello sir,
    thanks for giving that type of information. Really enjoyed this blog post. Really looking forward to reading more. Much obliged.
    digital marketing company in delhi

    ReplyDelete
  36. Thanks for the article may be useful for everything
    App Developers in Noida

    ReplyDelete
  37. This is really great work. Thank you for sharing such useful information here in the blog. This really is excellent function. Thanks, with regard to discussing this kind of helpful info within your blog. You can now click here construction company westchester county Thanks greatly with regard to good publish.

    ReplyDelete
  38. I feel happy about and learning more about this topic. keep sharing your information regularly for my future reference. This content creates a new hope and inspiration with in me. Thanks for sharing article like this. the information which you have provided is better then other blog.
    Best IELTS Coaching in Dwarka

    ReplyDelete
  39. Hey Admin,
    I really appreciate your effort of sharing information with us. Your article never fails to add useful information to my knowledge. Thanks for sharing with us.
    UI Development Services

    ReplyDelete
  40. I found a lot of valuable information in your article, it’s really helpful for me, am suggest to my all dear friend to visit this blog and collect this valuable information, I really happy to say this keep sharing this type of blog, I really like to read this, I hope I will see you again with this type of valuable information, thank you so much for read my comment I will suggest to you all comment reader please deeply read this blog and collect this useful information, if any one searching the website designing company in India please come on my website ogeninfo, we are working in 5 year on this field, we are complete your all type project like website designing & web development and PPC.
    Web Designing Company in Delhi

    ReplyDelete
  41. Your blog give me a lot of valuable information, I really like to read your article, I will suggest to my all dear friend to visit this blog and collect this useful information, keep sharing like this type useful blog, I am really happy to say this am really enjoy to read this article, thank you so much for share this helpful information with us, if any one need a shipping company in India to shift you product, we are shift you product with care and faster if you need it so please come on my website Yhcargoindia, thanks to read my comment.
    Sea Freight Company in India

    ReplyDelete

  42. Thank you for this excellent read!! I definitely loved every little bit of it. Cheers for the information.
    This is the perfect blog for anyone who wants to know about this topic.
    You know so much it's almost hard to argue with you
    Buy Products TreasureBox

    ReplyDelete
  43. Top Law Firms in the United Kingdom When we need a law firm, we have the expectation that this law firm will support us and guide us in such a way that we can find out any solution under the legal framework. But the problem generates when we cannot find such a legal firm or law firm with such specialties that are required for that specific issue.

    ReplyDelete
  44. Currency Converter Thanks for sharing your info. I truly appreciate your efforts and I am waiting for your next write ups thank you once again...

    ReplyDelete
  45. Map of Distance Map of Distance contains over 85,000 records of world climate data (historical weather averages) from a wide range of sources. At present, all place names and COUNTRIES are shown with the names they had at the time the data was recorded. Map of Distance provide the most reliable and accurate weather & temperature information well into the new millennium.

    ReplyDelete
  46. may be useful for all, helpful article once and pardon me permission to share also here :

    Cara menurunkan asam lambung
    Obat klep jantung bocor herbal

    ReplyDelete
  47. Map of Distance Map of Distance helps you to find the Driving Distance, how many miles from a city to an another city on map. Distance between cities or 2 locations are measured in both kilometers, miles and nautical miles at the same time.

    ReplyDelete
  48. http://tech.winstonsalem.com/2012/11/wfu-cancer-research-sparks-cover-story.html

    ReplyDelete
  49. Defective Boiler Thanks for sharing your info. I truly appreciate your efforts and I am waiting for your next write ups thank you once again.

    ReplyDelete
  50. Housing Disrepair Claims Hello there, I found your blog by means of Google even as searching for a related matter, your website came up, it appears good. I’ve bookmarked it in my google bookmarks.

    ReplyDelete
  51. Best app To watch Latest films And movies online cyberflix tv

    ReplyDelete
  52. know how to log into jiofi router to change wifi name and password. jiodongle.local.html

    ReplyDelete
  53. Defective Roofing and Gutters Hello there, simply was aware of your blog through Google, and located that it’s really informative. I am gonna be careful for brussels. I’ll be grateful if you proceed this in future. Numerous other folks will probably be benefited from your writing.
    Cheers!

    ReplyDelete
  54. Thank you so much for share this type of articles keeps the users interest in this article, I really like to read this awesome blog.
    Top 5 Website Development Company | Digital Marketing Company in Delhi

    ReplyDelete
  55. Billy Ray Cyrus Net Worth Hello there! This post couldn’t be written any better! Reading this post reminds me of my previous room mate! He always kept talking about this. I will forward this page to him. Pretty sure he will have a good read. Many thanks for sharing!

    ReplyDelete
  56. Nice and interesting post. Thank You! For sharing such a great article, I like to read your information you have mentioned in this article are helpful for me.
    best ielts coaching center in gurgaon

    ReplyDelete
  57. Usually I never comment on blogs but your article is so convincing that I never stop myself to say something about it. You’re doing a great job Man,Keep it up.
    study in ireland consultants in delhi

    ReplyDelete
  58. Law firmsFind Your All Type Claims Information
    Find Your Legal Case Solicitor.
    Find Insurance Companies.
    Search Rehab and Physio Doctor.
    Find Your Online Short Courses and Degree.
    Find Adviser for Mortgage.
    Find Cheap Auto Insurance.

    ReplyDelete
  59. Hi, It's a great a post. Thanks For Sharing me a valuable and informative information.
    Experience the work of highly trained Bespoke Tailors only at Sartojiva. Our wide varieties of suits are made of fabric that is of very high quality which is guaranteed to give you complete functionality.

    ReplyDelete
  60. Online DegreeFind Your All Type Claims Information
    Find Your Legal Case Solicitor.
    Find Insurance Companies.
    Search Rehab and Physio Doctor.
    Find Your Online Short Courses and Degree.
    Find Adviser for Mortgage.
    Find Cheap Auto Insurance.

    ReplyDelete
  61. Find a company that offer best custom essay writing service that guarantees you research competence. A company that provides you with only custom term paper writing service with exemplary research abilities, and also endow them with an assortment of research facilities.

    ReplyDelete
  62. Currency ConverterFind Your All Types of Travel Information
    Find Currency Converter.
    Find Temperature & Climate Data.
    Find Driving Distance between cities.
    Find Flight Distance between two destinations.
    Find Major cities around the world.

    ReplyDelete
  63. Then again, you could have a go at utilizing the absolute most 192.168.1.254 login every now and again observed username and secret word mixes. We have arranged a rundown of these further down the page, however this will require some experimentation.

    ReplyDelete
  64. The strategy for "group stating" is utilized on some more drawn out emotional arrangement (normally running up to a limit of around 13 scenes) . The thought for such a program might be created "in-house" by one of the systems; it could begin from an autonomous generation organization (some of the time a result of both). For instance, the BBC's long-running drama free tv series downloads no registration EastEnders is completely a BBC creation, while its prominent dramatization Life on Mars was created by Kudos in relationship with the telecaster

    ReplyDelete
  65. Thank you so much for share this type of articles keeps the users interest in this article, I really like to read this awesome blog.
    Castor Seed Exporters, Drumstick Exporters

    ReplyDelete
  66. I am enjoy to read this, it’s provided me lot of information.

    With Indo American Health, you can choose the best hospital for Heart Treatment In India, where you will get the best care within your budget. You should not take a chance and treat your heart disease by giving us a call.

    ReplyDelete
  67. UBQGS(Ubai Bin Qaab Global Services) providing services for the students around the globe who are willing to learn Quran Online from any place. UBQGS has designed a comprehensive curriculum for online learning Quran and basics of islamic education. Our distance courses utilize common online learning tools, which is the best example of combining modern teaching methods. You will experience studying online islamic education classes in very innovative way.

    Our Services
    We are providing Our services to every individual anywhere in the world who has access to a high speed internet connection (DSL, Broadband) at lowest possible cost. Our complete courses include:
    - Quran Reading Education for Beginners
    - Tajweed Classes for Advance learners
    - Quran Translation
    - Basic Islamic teachings
    - Memorization of Holy Quran

    Students feel free to register now.

    ReplyDelete
  68. Temperature & Climate DataFind Your All Types of Travel Information
    Find Currency Converter.
    Find Temperature & Climate Data.
    Find Driving Distance between cities.
    Find Flight Distance between two destinations.
    Find Major cities around the world.

    ReplyDelete
  69. Driving Distance between citiesFind Your All Types of Travel Information
    Find Currency Converter.
    Find Temperature & Climate Data.
    Find Driving Distance between cities.
    Find Flight Distance between two destinations.
    Find Major cities around the world.

    ReplyDelete
  70. We understand that Research Paper for Sale Online is an important piece of writing. So, don't take the risk of presenting a paper that you are not sure will earn you grades. Take advantage of our Cheap Custom Essay Writing Services expertise. This is a chance to climb higher on the grading criteria.

    ReplyDelete
  71. Nice and interesting post. Thank You! For sharing such a great article, I like to read your information you have mentioned in this article are helpful for me.
    best ielts coaching center in gurgaon

    ReplyDelete
  72. ihotelsbooking.com Thanks for ones marvelous posting! I definitely enjoyed reading it, you are a great author. I will be sure to bookmark your blog and definitely will come back later on. I want to encourage you to ultimately continue your great work, have a nice day!

    ReplyDelete
  73. Our top-notch writers have access to peer-reviewed articles, Essay Writer Services and online databases that are essential in writing Best Custom Writing Services on any chosen topic.

    ReplyDelete
  74. Flight Distance between two destinationsFind Your All Types of Travel Information
    Find Currency Converter.
    Find Temperature & Climate Data.
    Find Driving Distance between cities.
    Find Flight Distance between two destinations.
    Find Major cities around the world.

    ReplyDelete
  75. The first thing I look for is personalization. This is so easy, I really enjoyed this post. Check out this unrelated link. I wrote about the IELTS.
    Best IELTS Coaching in Dwarka

    ReplyDelete
  76. Hire our WooCommerce developer and programmers and get the best WooCommerce development services. we are a top-notch Woocommerce Development Company in India & USA. +91-9806724185 or Contact@expresstechsoftwares.com

    ReplyDelete
  77. Dank vapes are fast becoming a staple substitution for marijuana in homes. Although vape carts remain an illegal comodity in many states across the USA and parts of the world, Dank vape carts suppliers continue to promote the use of these vape carts in these states by delivering discreetly over the mail.
    vape danks , and other carts such as Mario carts , stiizy pods,moonrock carts, exotic carts are often criticized for not scoring a pass in laboratory test. However these carts remain the best vapes in the market and constitute the best vape flavors. Dank vapes in particular for over the years has scored the highest criticism on the market but also has made the highest sales for over the years.the most popular vapes products are so far the dank vapes and the most recommended vape is the moonrock carts.
    Dankwoods blunts and backwood prerolls are also a product of the dank company.
    Though the company is an illegally operating company with no official web account, dankwoods can be found all over the internets platforms such as instagram, facebook, and tweeter.
    Dankwoods prerolls constitute a 2gram mass of dank blunt and some aromatic dank flavors.
    Dankwoods price varies over the internet and cheapest dankwood prices are determined by the dankwoods suppliers. However buying dankwoods in bulk can always be facilitated over the web.

    ReplyDelete
  78. It is amazing and wonderful to visit your site.Thanks for sharing this information,this is useful to me...
    interior designers in chennai

    ReplyDelete
  79. TCA, being an online setup, resolves this concern of such aspirants and plays a critical role in saving time, money and energy costs of the aspirants.We are proud to win the trust of hundreds of students with our effectual strategies and powerful mechanism. You can come and join us as TCA Online is surely your gateway to bureaucracy.whatsapp call for
    more info +923133319144

    https://tcaonline.pk/

    Online CSS Academy,

    Online CSS Institute,

    Online CSS Preparation,

    Best CSS Academy,

    Best Online CSS Academy in Pakistan,

    Best CSS Academy in Pakistan,

    Best CSS Academy in Islamabad,

    Best CSS Academy in Lahore,

    Best CSS Academy in Karachi,

    Best CSS Academy in Peshawar,

    GK MCQs

    ReplyDelete
  80. If you are searching for a Dietitian In Delhi, Diets & More is where you can end your search. Dt. Shreya Katyal can provide customized diet plans that fit your body needs. She offers online consultation to her patients. To solve your dieting issues, you can call her or WhatsApp your query.

    ReplyDelete
  81. Do you require Annotated Bibliography Powerpoint Presentation from a credible and trusted writing company which guarantees high -quality articles for the client? It can be challenging to acquire secure and confidential Quality Research Papers from a writing company.

    ReplyDelete


  82. 192.168.1.254
    192.168.0.1

    192.168.1.1

    192.168.l.254
    Positive site, where did u come up with the information on this posting?I have read a few of the articles on your website now,

    ReplyDelete
  83. Your post was really helpful & most of my doubts were cleared.

    https://www.dezinecareers.com/

    ReplyDelete
  84. Nice article witten. It was really helpfull. Article

    ReplyDelete
  85. One unique characteristic of the firm's Custom Research Paper Services and College Paper Writing Services is that they offer the best market rates and actual research on all their Custom College Paper Writing Services.

    ReplyDelete